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Molecular Neurobiology Laboatory

게시물 검색
총 게시물 76 , 페이지 1 / 8

Discovery of Diphenyl Ether Derivatives as Novel BKCa Channel Activators: Structure-Activity Relationship, Cryo-EM Complex Structures, and In Vivo Animal Studies
  • AuthorSoo Bin Park, Na Young Lee, Eun-Young Lee, Subin Kim, Narasaem Lee, Eun Chae Roh, Yoon Gyoon Kim, Hee Jin Kim, Mi Sun Jin, Chul-Seung Park, Yong-Chul Kim
  • Year2025
  • SourceJournal of Medicinal Chemistry

CRBN modulates synuclein fibrillation via degradation of DNAJB1 in mouse model of Parkinson disease
  • AuthorUroos Akber, Jun-Hyung Jung, Heewoong Yoon, Jiwon Seo, Chul-Seung Park
  • Year2024
  • Sourcenpj Parkinson's Disease

Activation mechanism and novel binding sites of the BKCa channel activator CTIBD
  • AuthorNarasaem Lee, Subin Kim, Na Young Lee, Heeji Jo, Pyeonghwa Jeong, Haushabhau S Pagire, Suvarna H Pagire, Jin Hee Ahn, Mi Sun Jin, Chul-Seung Park
  • Year2024
  • SourceLife Science Alliance

Enhanced homeostatic sleep response and decreased neurodegenerative proteins in cereblon knock-out mice
  • AuthorJun-Hyung Jung, Jinhong Kim, Uroos Akber, Na Young Lee, Jeong-won Baek, Jieun Jung, Mincheol Park, Jiseung Kang, Seungje Jeon, Chul-Seung Park, Tae Kim
  • Year2024
  • SourceCommunications Biology

Effects of cereblon on stress-activated redox proteins and core behavior
  • AuthorUroos Akber, Sunhwa Bong, Zee-Yong Park, Chul-Seung Park
  • Year2022
  • SourceBrain Research

Discovery and characterization of a potent activator of the BKCa channel that relives overactive bladder syndrome in rats
  • AuthorHeeji Jo, Eun Jung Bae, Narasaem Lee, Jae Won Kwon, Suhan Cho, Sung Joon Kim, Jin Hee Ahn, Chul-Seung Park
  • Year2022
  • SourceEuropean Journal of Pharmacology

Cereblon Regulates the Proteotoxicity of Tau by Tuning the Chaperone Activity of DNAJA1
  • AuthorUroos Akber, Heeji Jo, Seungje Jeon, Seung-Joo Yang, Sunhwa Bong, Sungsu Lim, Yun Kyung Kim, Zee-Yong Park, and Chul-Seung Park*
  • Year2021
  • SourceThe Journal of Neuroscience

Regulation of AMPK Activity by CRBN Is Independent of the Thalidomide-CRL4CRBN Protein Degradation Axis
  • AuthorSeung-Joo Yang, Seungje Jeon, Jeong Won Baek, Kwang Min Lee* and Chul-Seung Park*
  • Year2021
  • SourcePharmaceuticals

Ablation of CRBN induces loss of type I collagen and SCH in mouse skin by fibroblast senescence via the p38 MAPK pathway
  • AuthorSeungje Jeon, Yi-Seul Yoon, Hyoung Kyu Kim, Jin Han, Kwang Min Lee, Jung Eun Seol*, Steve K. Cho*, Chul-Seung Park*
  • Year2021
  • SourceAging

Identification and Characterization of a Novel Large-Conductance Calcium-Activated Potassium Channel Activator, CTIBD, and Its Relaxation Effect on Urinary Bladder Smooth Muscle
  • AuthorNarasaem Lee, Bong Hee Lim, Kyu-Sung Lee, Jimin Shin, Haushabhau S. Pagire, Suvarna H. Pagire, Jin Hee Ahn, Sung Won Lee, Tong Mook Kang, and Chul-Seung Park*
  • Year2021
  • SourceMOLECULAR PHARMACOLOGY
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