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Synthesis and biological evaluation of peripheral 5HT2B antagonists for liver fibrosis
  • AuthorJihyeon Yoon, Won-Il Choi, Won Hee Lee, Gwi Bin Lee, Byeong Wook Choi, Pyeongkeun Kim, Yerim Heo, Dong Gun Kim, Hyeon Ah Kim, Myung Ae Bae, Seong Soon Kim, Eun Young Lee, Chang-Myung Oh, Hyeok Jae Lee, Hyun Woo Kim, Wan Namkung, Hail Kim*, Jin Hee Ahn*
  • Year2025
  • SourceJ. Med. Chem. 2025, 68, 6493-6506

Synthesis and biological evaluation of peripheral HTR2A antagonists for colorectal cancer
  • AuthorMinhee Kim†, Jihyeon Yoon†, Jun Young Choi, Geumi Park, Jae-Eon Lee, Gwi Bin Lee, Byeong Wook Choi, Pyeongkeun Kim, Hail Kim, Chang-Myung Oh, Myung Ae Bae, Seong Soon Kim, Eun Young Lee, Hyeok Jae Lee, Yunmin Kim, Hyun Woo Kim, Hohjai Lee*,Yong Hyun Jeon*, Jin Hee Ahn*
  • Year2025
  • SourceJ. Med. Chem. 2025, 68, 1716-1730

Discovery of Pyrazolopyrimidine Derivatives as Aryl Hydrocarbon Receptor Antagonists for Colorectal Cancer Immunotherapy
  • AuthorByeong Wook Choi, Jae-Eon Lee, Da Bin Jeon, Pyeongkeun Kim, Gwibin Lee, Saravanan Parameswaran, Ji Yun Jang, Gopalakrishnan Chandrasekaran, Su-Bin Cho, Geumi Park, Jihyun Yoon, Yerim Heo, Donggun Kim, Seong Soon Kim, Jung Yoon Yang, Myung Ae Bae, Yong Hyun Jeon*, Seok-Yong Choi*, Jin Hee Ahn*
  • Year2025
  • SourceUnder revision

Discovery of Novel Oxadiazolone Derivatives for Dravet Syndrome
  • AuthorDong Gun Kim, Kyu-Seok Hwang, Se Hwan Ahn, Seong Soon Kim, Yuji Son, Sung Bum Park, Won Hoon Jung, Dae-Seop Shin, Sung Hee Cho, Byeong Wook Choi, Pyungkeen Kim, Yerim Heo, Minhee Kim, Jung Yoon Yang, Kyeong-Ryoon Lee, Hyang-Ae Lee, Jihun Kim, Hoon-Chul Kang, Ki Young Kim*, Myung Ae Bae*, Jin Hee Ahn*
  • Year2025
  • Sourcein preparation

SMEPPI: An indenone derivative that selectively inhibits M1 macrophage activation and enhances phagocytic activity.
  • AuthorJi Hyun Oh, Mi Gyeong Jeong, Soheun Lee, Jihae Lim, Jio Kang, Myung Ae Bae, Jin Hee Ahn, Jeong-Ho Hong, Eun Sook Hwang*
  • Year2025
  • SourceBiomedicine & Pharmacotherapy, 2025, 183, 117856

A composition for preventing or treating macular degeneration comprising pyruvate dehydrogenase kinase inhibitor
  • AuthorPark, Dong Ho; Lee, In-Kyu; Ahn, Jin Hee; Pagire, Haushabhau Shivaji; Pagire, Suvarna Haushabhau
  • Year2025
  • SourceWO2025005691

NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF
  • AuthorHS Pagire, IK Lee, JH Jeon, SH Pagire, PK kim, CJ Oh, YH Jeon, KH Son and Jin Hee Ahn
  • Year2024
  • SourceWO 2024071629

Discovery of a peripheral 5HT2A antagonist as a clinical candidate for Metabolic Dysfunction-Associated Steatohepatitis
  • AuthorHaushabhau S. Pagire, Suvarna H Pagire, Byung-kwan Jeong, Won-il Choi, Chang Joo Oh, Chae Won Lim, Minhee Kim, Jihyeon Yoon, Seong Soon Kim, Myung Ae Bae, Jae-Han Jeon, Sungmin Song, Hee Jong Lee, Eun Young Lee, Peter Goughnour, Dooseop Kim, In-Kyu Lee, Rohit Loomba, Hail Kim*, Jin Hee Ahn*
  • Year2024
  • SourceNature Communications 2024, 15, 645

Design, synthesis, and biological evaluation of new 2,6,7-substituted purine derivatives as Toll-like receptor 7 agonists for intranasal vaccine adjuvants
  • AuthorMorgan Kim, Kyungseob Noh, Pyeongkeun Kim, Jaeho Kim, Byeong Wook Choi, Ravi Singh, Junho Choi, Soo Bong Han, Seong Soon Kim, Eun-Young Lee, Myung Ae Bae, Daeho Shin, Meehyein Kim*, Jin Hee Ahn*
  • Year2024
  • SourceJ. Med. Chem. 2024, 67, 9389-9405

Discovery of Novel Arylpyridine Derivatives for Motile Ciliogenesis
  • AuthorGwi Bin Lee, Gopalakrishnan Chandrasekaran, Hee-Joong Kim, Pyeongkeun Kim,, Jihyeon Yoon, Byeong Wook Choi, So-Hyun Lee, Sang-Yong Lee, Dae-Seop Shin, Byung Hoi Lee, Myung Ae Bae, Peter Goughnour, Eun Young Choi, Seok-Yong Choi* and Jin Hee Ahn*
  • Year2024
  • SourceEur J Med Chem 2024, 277, 116764
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