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Synthesis and biological evaluation of peripheral 5HT2B antagonists for liver fibrosis
Author
Jihyeon Yoon, Won-Il Choi, Won Hee Lee, Gwi Bin Lee, Byeong Wook Choi, Pyeongkeun Kim, Yerim Heo, Dong Gun Kim, Hyeon Ah Kim, Myung Ae Bae, Seong Soon Kim, Eun Young Lee, Chang-Myung Oh, Hyeok Jae Lee, Hyun Woo Kim, Wan Namkung, Hail Kim*, Jin Hee Ahn*
Year
2025
Source
J. Med. Chem. 2025, 68, 6493-6506
Synthesis and biological evaluation of peripheral HTR2A antagonists for colorectal cancer
Author
Minhee Kim†, Jihyeon Yoon†, Jun Young Choi, Geumi Park, Jae-Eon Lee, Gwi Bin Lee, Byeong Wook Choi, Pyeongkeun Kim, Hail Kim, Chang-Myung Oh, Myung Ae Bae, Seong Soon Kim, Eun Young Lee, Hyeok Jae Lee, Yunmin Kim, Hyun Woo Kim, Hohjai Lee*,Yong Hyun Jeon*, Jin Hee Ahn*
Year
2025
Source
J. Med. Chem. 2025, 68, 1716-1730
Discovery of Pyrazolopyrimidine Derivatives as Aryl Hydrocarbon Receptor Antagonists for Colorectal Cancer Immunotherapy
Author
Byeong Wook Choi, Jae-Eon Lee, Da Bin Jeon, Pyeongkeun Kim, Gwibin Lee, Saravanan Parameswaran, Ji Yun Jang, Gopalakrishnan Chandrasekaran, Su-Bin Cho, Geumi Park, Jihyun Yoon, Yerim Heo, Donggun Kim, Seong Soon Kim, Jung Yoon Yang, Myung Ae Bae, Yong Hyun Jeon*, Seok-Yong Choi*, Jin Hee Ahn*
Year
2025
Source
Under revision
Discovery of Novel Oxadiazolone Derivatives for Dravet Syndrome
Author
Dong Gun Kim, Kyu-Seok Hwang, Se Hwan Ahn, Seong Soon Kim, Yuji Son, Sung Bum Park, Won Hoon Jung, Dae-Seop Shin, Sung Hee Cho, Byeong Wook Choi, Pyungkeen Kim, Yerim Heo, Minhee Kim, Jung Yoon Yang, Kyeong-Ryoon Lee, Hyang-Ae Lee, Jihun Kim, Hoon-Chul Kang, Ki Young Kim*, Myung Ae Bae*, Jin Hee Ahn*
Year
2025
Source
in preparation
SMEPPI: An indenone derivative that selectively inhibits M1 macrophage activation and enhances phagocytic activity.
Author
Ji Hyun Oh, Mi Gyeong Jeong, Soheun Lee, Jihae Lim, Jio Kang, Myung Ae Bae, Jin Hee Ahn, Jeong-Ho Hong, Eun Sook Hwang*
Year
2025
Source
Biomedicine & Pharmacotherapy, 2025, 183, 117856
A composition for preventing or treating macular degeneration comprising pyruvate dehydrogenase kinase inhibitor
Author
Park, Dong Ho; Lee, In-Kyu; Ahn, Jin Hee; Pagire, Haushabhau Shivaji; Pagire, Suvarna Haushabhau
Year
2025
Source
WO2025005691
NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF
Author
HS Pagire, IK Lee, JH Jeon, SH Pagire, PK kim, CJ Oh, YH Jeon, KH Son and Jin Hee Ahn
Year
2024
Source
WO 2024071629
Discovery of a peripheral 5HT2A antagonist as a clinical candidate for Metabolic Dysfunction-Associated Steatohepatitis
Author
Haushabhau S. Pagire, Suvarna H Pagire, Byung-kwan Jeong, Won-il Choi, Chang Joo Oh, Chae Won Lim, Minhee Kim, Jihyeon Yoon, Seong Soon Kim, Myung Ae Bae, Jae-Han Jeon, Sungmin Song, Hee Jong Lee, Eun Young Lee, Peter Goughnour, Dooseop Kim, In-Kyu Lee, Rohit Loomba, Hail Kim*, Jin Hee Ahn*
Year
2024
Source
Nature Communications 2024, 15, 645
Design, synthesis, and biological evaluation of new 2,6,7-substituted purine derivatives as Toll-like receptor 7 agonists for intranasal vaccine adjuvants
Author
Morgan Kim, Kyungseob Noh, Pyeongkeun Kim, Jaeho Kim, Byeong Wook Choi, Ravi Singh, Junho Choi, Soo Bong Han, Seong Soon Kim, Eun-Young Lee, Myung Ae Bae, Daeho Shin, Meehyein Kim*, Jin Hee Ahn*
Year
2024
Source
J. Med. Chem. 2024, 67, 9389-9405
Discovery of Novel Arylpyridine Derivatives for Motile Ciliogenesis
Author
Gwi Bin Lee, Gopalakrishnan Chandrasekaran, Hee-Joong Kim, Pyeongkeun Kim,, Jihyeon Yoon, Byeong Wook Choi, So-Hyun Lee, Sang-Yong Lee, Dae-Seop Shin, Byung Hoi Lee, Myung Ae Bae, Peter Goughnour, Eun Young Choi, Seok-Yong Choi* and Jin Hee Ahn*
Year
2024
Source
Eur J Med Chem 2024, 277, 116764
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