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Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty liver disease
  • AuthorEun Jung Bae, Won Gun Choi, Haushabhau S. Pagire, Suvarna H Pagire, Saravanan Parameswaran, Jun-Ho Choi, Jihyeon Yoon, Jin Sook Song, Myung Ae Bae, Mijin Kim, Jae-Han Jeon, In-Kyu Lee, Hail Kim*, Jin Hee Ahn*
  • Year2020
  • SourceJ. Med. Chem. 2020, in press

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT2A Antagonists for Nonalcoholic Fatty Liver Disease
  • AuthorMinhee Kim, Inseon Hwang, Haushabhau S. Pagire, Suvarna H Pagire, Wonsuk Choi, Won Gun Choi, Jihyeon Yoon, Won Mi Lee, Jin Sook Song, Eun Kyung Yoo, Seungmi Lee, Mijin Kim, Myung Ae Bae, Dooseop Kim, Heejong Lee, Eun-Young Lee, Jae-Han Jeon, In Kyu Lee, Hail Kim*, Jin Hee Ahn*
  • Year2020
  • SourceJ. Med. Chem. 2020, 63, 4171-4182

Identification of novel anti-melanogenic agents using a zebrafish model
  • AuthorSe Hwan Ahn, Kyu-Seok Hwang, Dae-Seop Shin, Seong Soon Kim, Jung Yoon Yang, Myung Ae Bae*, Jin Hee Ahn*
  • Year2020
  • SourceBioorg. & Med. Chem. Lett. 2020, 30,127201

Optimization of cyclic sulfamide derivatives as 11beta-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury
  • AuthorJeong Hyun Lee, Ju Hwan Bok, Sung Bum Park, Haushabhau S. Pagire, Yoon-Ju Na, Won Hoon Jung, Jin Sook Song, Nam Sook Kang, Ho Won Seo, Byung Ho Lee, Ki Young Kim*, Jin Hee Ahn*
  • Year2020
  • SourceBioorg. & Med. Chem. Lett. 2020, 30, 126787

Multimodal imaging probe development for pancreatic β-cells: from fluorescence to PET
  • AuthorNam-Young Kang, Jung Yeol Lee, Sang Hee Lee, In Ho Song, Yong Hwa Hwang, Min Jun Kim,Wut Hmone Phue, Bikram Keshari Agrawalla, Si Yan Diana Wan, Janise Lalic, Sung-Jin Park, Jong-Jin Kim, Haw-Young Kwon, So Hee Im, Myung Ae Bae, Jin Hee Ahn, Chang Siang Lim, Adrian Kee Keong Teo, Sunyou Park, Sang Eun Kim, Byung Chul Leel, Dong Yun Lee, Young-Tae Chang *
  • Year2020
  • SourceJ. Am. Chem. Soc. 2020, 147, 3430-3439

TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
  • AuthorHyun-Kyoung Kim, Kashi Raj Bhattarai, Raghu Patil Junjappa, Jin Hee Ahn, Suvarna H. Pagire, Hyun Ju Yoo, Jaeseok Han, Duckgue Lee, Kyung-Woon Kim, Hyung-Ryong Kim, Han-Jung Chae*
  • Year2020
  • SourceNature Communications 2020, 11, 4012

Structural basis for the inhibition of PDK2 by novel ATP- and lipoylbinding site targeting compounds
  • AuthorJihoon Kang, Haushabhau S. Pagire, Donguk Kang, Yo Han Song, In Kyu Lee, Kang Taek Lee, Chin-Ju Park, Jin Hee Ahn, Jungwook Kim*
  • Year2020
  • SourceBiochemical and Biophysical Research Communications 2020, 527, 778-784

Efficacy and pharmacokinetics evaluation of 4-(2-chloro-4-fluorobenzyl)-3-(2-thienyl)-1,2,4-oxadiazol-5(4H)-one (GM-90432) as an anti-seizure agent
  • AuthorKyu-Seok Hwang, Hyemin Kan, Seong Soon Kim, Jin Sil Chae, Jung Yoon Yang, Dae-Seop Shin, Se Hwan Ahn, Jin Hee Ahn, Jin-Hwa Cho, Il-Sung Jang, Cheol-Hee Kim, and Myung Ae Bae*
  • Year2020
  • SourceNeurochemistry International 2020, 141, 104870

Potent Small-molecule Inhibitors Targeting Acetylated Microtubules as Anticancer Agents against Triple-negative Breast Cancer
  • AuthorAhreum Kwon, Gwi Bin Lee, Taein Park, Jung Hoon Lee, Panseon Ko, Eunae You, Jin Hee Ahn, Soo Hyun Eom, Sangmyung Rhee*, and Woo Keun Song*
  • Year2020
  • SourceBiomedicine 2020 8, 338

A Novel Selective 11-HSD1 Inhibitor, (E)-4-(2-(6-(2,6-Dichloro-4-(Trifluoromethyl)Phenyl)-4-Methyl-1,1-Dioxido-1,2,6-Thiadiazinan-2-yl)Acetamido)Adamantan-1-Carboxamide (KR-67607), Prevents BAC-Induced Dry Eye Syndrome
  • AuthorYoon-Ju Na, Kyoung Jin Choi, Won Hoon Jung, Sung Bum Park, Sein Kang, Jin Hee Ahn and Ki Young Kim*
  • Year2020
  • SourceInt. J. Mol. Sci. 2020, 21, 3729
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