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Laboratory of Drug Discovery

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Urinary bladder-relaxant effect of kurarinone depending on potentiation of large-conductance Ca2+-activated K+ channels
  • AuthorSojung Lee, Mee Ree Chae, Byoung-Cheol Lee, Yong-Chul Kim, Jae Sue Choi, Sung Won Lee, Jae Hoon Cheong, Chul-Seung Park
  • Year2016/8/1
  • SourceMolecular pharmacology

Subdermal flexible solar cell arrays for powering medical electronic implants
  • AuthorKwangsun Song, Jung Hyun Han, Taehoon Lim, Namyun Kim, Sungho Shin, Juho Kim, Hyuck Choo, Sungho Jeong, Yong‐Chul Kim, Zhong Lin Wang, Jongho Lee
  • Year2016/7
  • SourceAdvanced healthcare materials

Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening
  • AuthorMyoung Eun Jung, Byung Jin Byun, Hye-Mi Kim, Joo Yun Lee, Jin-Hee Park, Nari Lee, You Hwa Son, Sang Un Choi, Kyung-Min Yang, Seong-Jin Kim, Kwangho Lee, Yong-Chul Kim, Gildon Choi
  • Year2016/6/1
  • SourceBioorganic & medicinal chemistry letters

Homology modeling and molecular docking studies of Drosophila and Aedes sex peptide receptors
  • AuthorJeong-hyun Kim, Soo-Kyung Kim, Jae-Hyuk Lee, Young-Joon Kim, William A Goddard III, Yong-Chul Kim
  • Year2016/5/1
  • SourceJournal of Molecular Graphics and Modelling

5‐diphenylacetamido‐indirubin‐3′‐oxime as a novel mitochondria‐targeting agent with anti‐leukemic activities
  • AuthorJu Han Song, Jung‐Eun Lee, Kyung‐Min Cho, Su‐Ho Park, Hyeoung‐Joon Kim, Yong‐Chul Kim, Tae Sung Kim
  • Year2016/5
  • SourceMolecular carcinogenesis

Validation of a liquid chromatography-triple quadrupole mass spectrometric method for the determination of 5-nitro-5'-hydroxy-indirubin-3'-oxime (AGM-130) in human plasma and its application to microdose clinical trial.
  • AuthorMin‐Ho Park, Yun Young Lee, Kyung Hee Cho, Sookie La, Hee Joo Lee, Dong‐Seok Yim, Sooho Ban, Moon‐Young Park, Yong‐Chul Kim, Yoon‐Gyoon Kim, Young G Shin
  • Year2016/3
  • SourceBiomedical Chromatography

Myeloid-derived suppressor cells are controlled by regulatory T cells via TGF-β during murine colitis
  • AuthorCho-Rong Lee, Yewon Kwak, Taewoo Yang, Jung Hyun Han, Sang-Heon Park, B Ye Michael, Wongeun Lee, Kyu-Young Sim, Jung-Ah Kang, Yong-Chul Kim, Sarkis K Mazmanian, Sung-Gyoo Park
  • Year2016/12/20
  • SourceCell reports

Discovery and structure–activity relationship studies of quinolinone derivatives as potent IL-2 suppressive agents
  • AuthorSeung-Hwa Kwak, Jung-Ah Kang, Minjeong Kim, So-Deok Lee, Jin-Hee Park, Sung-Gyoo Park, Hyojin Ko, Yong-Chul Kim
  • Year2016/11/1
  • SourceBioorganic & medicinal chemistry

The discovery of 2, 5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3
  • AuthorSun-Mi Lee, Kyoung Bin Yoon, Hyo Jeong Lee, Jiwon Kim, You Kyoung Chung, Won-Jea Cho, Chisato Mukai, Sun Choi, Keon Wook Kang, Sun-Young Han, Hyojin Ko, Yong-Chul Kim
  • Year2016/11/1
  • SourceBioorganic & medicinal chemistry

Pyrazolodiazepine derivatives with agonist activity toward Drosophila RYamide receptor
  • AuthorYeu Kyung Yoon, Jung Ha Kim, Jeong-hyun Kim, Jae-Young Kwon, Yong-Chul Kim, Young-Joon Kim, Zee-Yong Park
  • Year2016/10/15
  • SourceBioorganic & medicinal chemistry letters
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