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Structural-function Discovery Lab.

Human PDK2 complexed with an allosteric inhibitor

작성자Structure-Function Discovery Lab.  조회수44 등록일2020-09-30
6lil_assembly-1.jpeg [59.7 KB]
PDB: 6LIL (Crystal structure of human PDK2 complexed with an allosteric inhibitor compound 8c)
Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds
Author : Jihoon Kang, Haushabhau S. Pagire, Donguk Kang, Yo Han Song, In Kyu Lee, Kang Taek Lee, Chin-Ju Park, Jin Hee Ahn, and Jungwook Kim
Biochem Biophys Res Commun. 2020 Jun 30;527(3):778-784. doi: 10.1016/j.bbrc.2020.04.102
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